(when radiolabelled) Indicated for diagnostic PET imaging of the myocardium under rest or pharmacologic stress conditions to evaluate myocardial perfusion in patients with suspected or existing coronary artery disease Label.Īs a gas, ammonia is a natural byproduct and respiratory stimulant.Indicated for use as a smelling salt to treat or prevent fainting.Type Small Molecule Groups Approved Synonyms Not Available Pharmacology Indication It is proposed that human adults produce about 1000 mmol of ammonia daily, most of which undergoes excretion in the urine. It is present in normally present in all tissues constituting a metabolic pool, where it is mostly taken up by glutamic acid and take part in transamination and other reactions, including the synthesis of protein by the Krebs-Hanseleit cycle in the liver 5.
Ammonia is a natural byproduct of biological and chemical reactions, including decomposition of organic matter, including plants, animals, and animal wastes. The radiolabelled form of ammonia, ammonia N 13, is intravenously administered as a radioactive diagnostic agent for Positron Emission Tomography (PET) imaging of the myocardium to evaluate myocardial perfusion. Ammonia gas has been used in the clinical setting as a respiratory stimulant to prevent fainting. Although ammonia is used as a food additive in the anhydrous form and serves as a starting material in pharmaceutical and commercial products, it is caustic and hazardous when concentrated. It is a colorless gas with a pungent smell, and become NH4, or ammonium ion, when in water. Kenalog Generic Name Ammonia DrugBank Accession Number DB11118 BackgroundĪmmonia is a naturally-occurring compound with a chemical formula NH3 and structure of trigonal pyramidal geometry.